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PAX2 Polyclonal Antibody

Product Specifications

Background

PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor suppressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. Alternative splicing of this gene results in multiple transcript variants.

Abbreviation

PAX2

UniProt

Q02962

Host

Rabbit

Reactivity

Human; Mouse

Immunogen

Synthetic peptide of human PAX2

Target

FSGS7; Paired box 2; Paired box gene 2; paired box homeotic gene 2; paired box protein 2; Paired box protein Pax 2; Paired box protein Pax-2; Paired box protein Pax2; PAPRS; Pax 2

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB

Field of Research

Cancer; Epigenetics and Nuclear Signaling; Developmental Biology; Neuroscience

Purification

Antigen affinity purification

Concentration

0.48 mg/mL

Dilution

WB 1:500-1:2000

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

45 kDa

Observed Molecular Weight

Refer to figures

Isotype

IgG

Available Sizes

Curated Selection

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