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DNA2 Polyclonal Antibody

Product Specifications

Background

This gene encodes a member of the DNA2/NAM7 helicase family. The encoded protein is a conserved helicase/nuclease involved in the maintenance of mitochondrial and nuclear DNA stability. Mutations in this gene are associated with autosomal dominant progressive external ophthalmoplegia-6 (PEOA6) and Seckel syndrome 8. Alternatively spliced transcript variants have been found for this gene.

Abbreviation

DNA2

UniProt

P51530

Host

Rabbit

Reactivity

Human

Immunogen

Fusion protein of human DNA2

Target

DNA replication ATP-dependent helicase-like homolog; DNA replication helicase 2 homolog; DNA replication helicase 2; yeast; homolog of; DNA replication helicase 2-like; DNA replication helicase/nuclease 2; DNA2; DNA2-like helicase; DNA2L; DNA2L; HDNA2; KIAA0083; PEOA6; SCKL8

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Cancer; Epigenetics and Nuclear Signaling

Purification

Antigen affinity purification

Concentration

0.6 mg/mL

Dilution

IHC 1:50-1:100

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG

Available Sizes

Frequently Asked Questions

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