SAV1 Polyclonal Antibody
Product Specifications
Background
WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein with two WW domains, a SARAH domain, and a coiled-coil region and is ubiquitously expressed in adult tissues. This protein binds to MST1 (mammalian sterile 20-like kinase 1) and promotes MST1-induced apoptosis. It has also been shown to bind to HAX1 (hematopoietic cell-specific protein 1 (HS1) -associated protein X-1) and to attenuate the anti-apoptotic effects of HAX1. Studies in human and mouse suggest this gene acts as a tumor suppressor.
Abbreviation
SAV1
UniProt
Q9H4B6
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Fusion protein of human SAV1
Target
1700040G09Rik;45 kDa WW domain protein; hWW 45; hWW45; Protein salvador homolog 1; salvador family WW domain containing protein 1; salvador homolog 1 (Drosophila) ; Salvador homolog 1; Salvador; Drosophila; homolog of; SAV 1; SAV; SAV1; SAV1; WW 45; WW domain containing; WW domain-containing adaptor 45; WW domain-containing protein; 45-KD; WW45; WW45 protein; WWP 4; WWP4
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Signal transduction
Purification
Antigen affinity purification
Concentration
1.32 mg/mL
Dilution
IHC 1:100-1:300
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG
Available Sizes
Frequently Asked Questions
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