HSD3B2 Polyclonal Antibody

The protein encoded by this gene is a bifunctional enzyme that catalyzes the oxidative conversion of delta (5) -ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. It plays a crucial role in the biosynthesis of all classes of hormonal steroids. This gene is predominantly expressed in the adrenals and the gonads. Mutations in this gene are associated with 3-beta-hydroxysteroid dehydrogenase, type II, deficiency. Alternatively spliced transcript variants have been found for this gene.

Hydroxy-Delta-5-Steroid Dehydrogenase; 3 Beta- And Steroid Delta-Isomerase 2;3 Beta-Hydroxysteroid Dehydrogenase/Delta 5-->4-Isomerase Type II; Short Chain Dehydrogenase/Reductase Family 11E; Member 2;3-Beta-HSD Adrenal And Gonadal Type;3-Beta-HSD II;3 Beta-Hydroxysteroid Dehydrogenase Type II; Delta 5-Delta 4-Isomerase Type II; 3 Beta-HSD Type II;3 Beta-Hydroxysteroid Dehydrogenase/Delta 5-->4-Isomerase Type 2;3-Beta-Hydroxy-Delta (5) -Steroid Dehydrogenase;3-Beta-Hydroxy-5-Ene Steroid Dehydrogenase.