MTHFD2 Polyclonal Antibody

Product Specifications

Background

This gene encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD. Alternative splicing results in two different transcripts, one protein-coding and the other not protein-coding. This gene has a pseudogene on chromosome 7.

Abbreviation

MTHFD2

UniProt

P13995

Host

Rabbit

Reactivity

Human; Mouse

Immunogen

Fusion protein of human MTHFD2

Target

Signal Transduction; Metabolism

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Signal Transduction; Metabolism

Purification

Antigen affinity purification

Concentration

1.14 mg/mL

Dilution

IHC 1:50-1:200

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG

Available Sizes

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