PTPA Polyclonal Antibody

Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.

Subunit B''; KIAA0044 ; MGC2184 ; Phosphotyrosyl phosphatase activator; PP2A; PP2A phosphatase activator ; PP2A subunit B'; PP2A subunit B' isoform PR53; PP2A subunit B' PR53 isoform ; PPP2R4; PR53 ; PR53 isoform; Protein phosphatase 2; regulatory subunit B-prime; Protein phosphatase 2A activator regulatory subunit 4; Protein phosphatase 2A regulatory subunit B' (PR 53) ; PTPA; PTPA; Serine/threonine protein phosphatase 2A regulatory subunit B' ; Serine/threonine-protein phosphatase 2A activator; Serine/threonine-protein phosphatase 2A regulatory subunit 4; Serine/threonine-protein phosphatase 2A regulatory subunit B''