SPACA1 Polyclonal Antibody
Product Specifications
Background
The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from infertile males. Furthermore, antibodies generated against the recombinant protein block in vitro fertilization. This protein localizes to the acrosomal membrane of spermatids and mature spermatozoa where it is thought to play a role in acrosomal morphogenesis and in sperm-egg binding and fusion, respectively.
Abbreviation
SPACA1
UniProt
Q9HBV2
Host
Rabbit
Reactivity
Human
Immunogen
Fusion protein of human SPACA1
Target
SACA1; SAMP32; SPACA1; Sperm acrosomal membrane-associated protein 32; Sperm acrosome membrane-associated protein 1
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cell Biology
Purification
Antigen affinity purification
Concentration
0.84 mg/mL
Dilution
IHC 1:50-1:100
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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