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RITA1 Polyclonal Antibody

Product Specifications

Background

Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. May play a role in neurogenesis.

Abbreviation

RITA1

UniProt

Q96K30

Host

Rabbit

Reactivity

Human

Immunogen

Fusion protein of human RITA1

Target

C12orf52 ; Chromosome 12 open reading frame 52 ; RBPJ interacting and tubulin associated 1; RBPJ interacting and tubulin associated protein 1; RBPJ-interacting and tubulin-associated protein; RITA; RITA

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Developmental biology; Neuroscience; Signal transduction; Stem cells

Purification

Antigen affinity purification

Concentration

1.02 mg/mL

Dilution

IHC 1:50-1:200

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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