PPM1M Polyclonal Antibody
Product Specifications
Background
PPM1M is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase was identified as an interacting protein of Rho guanine nucleotide exchange factors (PIX) . PIX proteins are regulators of p21/Cdc42/Rac1-activated kinase 1 (PAK1), a protein kinase mediating biological effects downstream of Rho GTPases. This phosphatase has been shown to block the effects of PAK, and thus inhibit actin stress fiber breakdown and morphological changes driven by cell division cycle 42 (CDC42) .
Abbreviation
PPM1M
UniProt
Q96MI6
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Fusion protein of human PPM1M
Target
FLJ32332; PP2C eta; PP2C-eta; PP2CE; PP2Ceta; PPM1M; PPM1M; protein phosphatase 1M (PP2C domain containing) ; Protein phosphatase 1M; Protein phosphatase 2C isoform eta
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Signal transduction
Purification
Antigen affinity purification
Concentration
1.74 mg/mL
Dilution
IHC 1:100-1:300
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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