TMED10 Polyclonal Antibody
Product Specifications
Background
This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8.
Abbreviation
TMED10
UniProt
P49755
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Fusion protein of human TMED10
Target
1110014C03Rik ;21 kDa transmembrane trafficking protein;21 kDa transmembrane-trafficking protein; MGC102351; p23; p24 family protein delta 1; p24 family protein delta-1; p24 (DELTA) ; p24delta; p24delta1; S31I125; S31III125; TMED 10; Tmed10; TMEDA; Tmp 21 I; Tmp 21; Tmp 21 I; Tmp-21-I; Transmembrane emp24 domain containing protein 10; Transmembrane emp24 domain-containing protein 10; Transmembrane emp24-like trafficking protein 10 (yeast) ; Transmembrane protein Tmp21; Transmembrane trafficking protein 21kD
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Neuroscience; Signal transduction
Purification
Antigen affinity purification
Concentration
1.14 mg/mL
Dilution
WB 1:1000-1:5000; IHC 1:50-1:200
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product Datasheet
https://789.bio/ea/0kxawd
Product MSDS
https://789.bio/eb/qDKCmT
Calculated Molecular Weight
25 kDa
Observed Molecular Weight
Refer to figures
Isotype
IgG
Available Sizes
Curated Selection
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