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MRPL42 Polyclonal Antibody

Product Specifications

Background

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a protein identified as belonging to both the 28S and the 39S subunits. Alternative splicing results in multiple transcript variants. Pseudogenes corresponding to this gene are found on chromosomes 4q, 6p, 6q, 7p, and 15q.

Abbreviation

MRPL42

UniProt

Q9Y6G3

Host

Rabbit

Reactivity

Human; Rat

Immunogen

Fusion protein of human MRPL42

Target

28S ribosomal protein S32;39S ribosomal protein L31;39S ribosomal protein L42; HSPC204 ; L31mt; L42mt; mitochondrial; Mitochondrial ribosomal protein L42; Mitochondrial ribosomal protein S32; MRP L31; MRP L42; MRP S32 ; MRP-L31; MRP-L42; MRP-S32; MRPL31 ; Mrpl42; MRPS32 ; PTD007 ; RM42; RPML31 ; S32mt

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Epigenetics and Nuclear Signaling; Metabolism

Purification

Antigen affinity purification

Concentration

1.14 mg/mL

Dilution

WB 1:1000-1:5000; IHC 1:50-1:200

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

17 kDa

Observed Molecular Weight

Refer to figures

Isotype

IgG

Available Sizes

Curated Selection

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