PCLAF Polyclonal Antibody
Product Specifications
Background
PCNA-binding protein that acts as a regulator of DNA repair during DNA replication. Following DNA damage, the interaction with PCNA is disrupted, facilitating the interaction between monoubiquitinated PCNA and the translesion DNA synthesis DNA polymerase eta (POLH) at stalled replisomes, facilitating the bypass of replication-fork-blocking lesions. Also acts as a regulator of centrosome number.
Abbreviation
PCLAF
UniProt
Q15004
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Fusion protein of human PCLAF
Target
HCV NS5A transactivated protein 9 ; HCV NS5A-transactivated protein 9; Hepatitis C virus NS5A transactivated protein 9; Hepatitis C virus NS5A-transactivated protein 9; KIAA0101; L5; NS5 ATP9; NS5ATP9; OEATC 1; OEATC; OEATC-1; OEATC1; Overexpressed in anaplastic thyroid carcinoma 1; p15 (PAF) ; p15PAF; PAF; PAF; PCNA associated factor; PCNA-associated factor
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Cell Biology; Metabolism
Purification
Antigen affinity purification
Concentration
0.84 mg/mL
Dilution
IHC 1:40-1:200
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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