PAPSS2 Polyclonal Antibody

Product Specifications

Background

Sulfation is a common modification of endogenous (lipids, proteins, and carbohydrates) and exogenous (xenobiotics and drugs) compounds. In mammals, the sulfate source is 3'-phosphoadenosine 5'-phosphosulfate (PAPS), created from ATP and inorganic sulfate. Two different tissue isoforms encoded by different genes synthesize PAPS. This gene encodes one of the two PAPS synthetases. Defects in this gene cause the Pakistani type of spondyloepimetaphyseal dysplasia. Two alternatively spliced transcript variants that encode different isoforms have been described for this gene.

Abbreviation

PAPSS2

UniProt

O95340

Host

Rabbit

Reactivity

Human; Mouse

Immunogen

Fusion protein of human PAPSS2

Target

3 prime phosphoadenosine 5 prime phosphosulfate synthase 2;3' phosphoadenosine 5' phosphosulfate synthase 2 ; ATP sulfurylase/adenosine 5' phosphosulfate kinase; ATP SULFURYLASE/ADENOSINE 5-PRIME PHOSPHOSULFATE KINASE 2; ATP sulfurylase/APS kinase 2; ATPSK2; Bifunctional 3' phosphoadenosine 5' phosphosulfate synthase 2; Bifunctional 3' phosphoadenosine 5' phosphosulfate synthethase 2; PAPS synthase 2; PAPS synthetase 2; PAPSS 2; PHOSPHOADENOSINE-PHOSPHOSULFATE SYNTHETASE 2; SK 2; SK2; Sulfurylase kinase 2