ZFYVE27 Polyclonal Antibody

This gene encodes a protein with several transmembrane domains, a Rab11-binding domain and a lipid-binding FYVE finger domain. The encoded protein appears to promote neurite formation. A mutation in this gene has been reported to be associated with hereditary spastic paraplegia, however the pathogenicity of the mutation, which may simply represent a polymorphism, is unclear.

Protrudin; RP11 459F3.2; SPG33 ; ZFY27; ZFYVE27; zinc finger FYVE domain containing 27 ; Zinc finger FYVE domain containing protein 27 ; Zinc finger FYVE domain-containing protein 27