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MTHFS Polyclonal Antibody

Product Specifications

Background

The protein encoded by this gene is an enzyme that catalyzes the conversion of 5-formyltetrahydrofolate to 5,10-methenyltetrahydrofolate, a precursor of reduced folates involved in 1-carbon metabolism. An increased activity of the encoded protein can result in an increased folate turnover rate and folate depletion. Three transcript variants encoding two different isoforms have been found for this gene.

Abbreviation

MTHFS

UniProt

P49914

Host

Rabbit

Reactivity

Human; Mouse

Immunogen

Fusion protein of human MTHFS

Target

10-methenyl-tetrahydrofolate synthetase;5 10 methenyl tetrahydrofolate synthetase;5;5 formyltetrahydrofolate cyclo ligase;5;10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) ;5-formyltetrahydrofolate cyclo-ligase; FLJ30410; HsT19268; Methenyl THF synthetase; Methenyl-THF synthetase; MTHFS; MTHFS

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Cancer; Metabolism; Signal transduction

Purification

Antigen affinity purification

Concentration

0.78 mg/mL

Dilution

IHC 1:40-1:200

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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