PPP1R1A Polyclonal Antibody

Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B) . Does not inhibit type-2 phosphatases.

I 1; I-1; I1; Inhibitor 1; IPP 1; IPP-1; IPP1; Ppp1r1a; PPR1A; Protein phosphatase 1 regulatory (inhibitor) subunit 1A; Protein phosphatase 1 regulatory subunit 1A; Protein phosphatase inhibitor 1