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PPP1R1A Polyclonal Antibody

Product Specifications

Background

Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B) . Does not inhibit type-2 phosphatases.

Abbreviation

PPP1R1A

UniProt

Q13522

Host

Rabbit

Reactivity

Human; Rat

Immunogen

Fusion protein of human PPP1R1A

Target

I 1; I-1; I1; Inhibitor 1; IPP 1; IPP-1; IPP1; Ppp1r1a; PPR1A; Protein phosphatase 1 regulatory (inhibitor) subunit 1A; Protein phosphatase 1 regulatory subunit 1A; Protein phosphatase inhibitor 1

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Cancer; Metabolism; Signal transduction

Purification

Antigen affinity purification

Concentration

1.02 mg/mL

Dilution

IHC 1:50-1:300

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG

Available Sizes

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