GSKIP Polyclonal Antibody
Product Specifications
Background
This gene encodes a protein that is involved as a negative regulator of GSK3-beta in the Wnt signaling pathway. The encoded protein may play a role in the retinoic acid signaling pathway by regulating the functional interactions between GSK3-beta, beta-catenin and cyclin D1, and it regulates the beta-catenin/N-cadherin pool. The encoded protein contains a GSK3-beta interacting domain (GID) in its C-terminus, which is similar to the GID of Axin. The protein also contains an evolutionarily conserved RII-binding domain, which facilitates binding with protein kinase-A and GSK3-beta, enabling its role as an A-kinase anchoring protein. Alternatively spliced transcript variants have been observed for this gene.
Abbreviation
GSKIP
UniProt
Q9P0R6
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Fusion protein of human GSKIP
Target
C14ORF129; Chromosome 14 open reading frame 129 ; GSK3-beta interaction protein; GSK3beta interaction protein; GSKIP; GSKIP; MGC4945; UPF0279
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cell Biology
Purification
Antigen affinity purification
Concentration
0.96 mg/mL
Dilution
IHC 1:40-1:200
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product Datasheet
https://789.bio/ea/0xp4rg
Product MSDS
https://789.bio/eb/ir1yb1
Isotype
IgG
Available Sizes
Curated Selection
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