RBM15 Polyclonal Antibody
Product Specifications
Background
RNA-binding motif protein 15 (RBM15) belongs to the SPEN protein family, which have repressor function in several signaling pathway, and may bind to RNA through interaction with spliceosome components. It was first described as a 5′ translocation partner of the MAL gene in t (1,22) (p13; q13) infant acute megakaryocytic leukemia, and it functions in murine hematopoiesis through modulating Notch-induced transcriptional activation, which play crucial roles in leukemogenesis. Decreasing RBM15 levels with RNA interference could inhibit the growth and proliferation, block the cell cycle, and induce apoptosis in CML cells.
Abbreviation
RBM15
UniProt
Q96T37
Host
Rabbit
Reactivity
Human
Immunogen
Fusion protein of human RBM15
Target
One twenty two protein; One-twenty two protein 1; OTT; OTT1; Putative RNA-binding protein 15; RBM15; RBM15; RNA binding motif protein 15; RNA-binding motif protein 15
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Epigenetics and Nuclear Signaling; Stem Cells
Purification
Antigen affinity purification
Concentration
1.2 mg/mL
Dilution
IHC 1:50-1:300
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product Datasheet
https://789.bio/ea/rdszm5
Product MSDS
https://789.bio/eb/unLOKK
Isotype
IgG
Available Sizes
Curated Selection
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