EXD2 Polyclonal Antibody
Product Specifications
Background
Exonuclease required for double-strand breaks resection and efficient homologous recombination. Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3'-5' exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks.
Abbreviation
EXD2
UniProt
Q9NVH0
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Fusion protein of human EXD2
Target
4930539P14Rik; C14orf114; C85658; DKFZp781A0133; DKFZp781L15100; Exd2; EXD2; EXDL2; Exonuclease 3''-5'' domain-containing protein 2; Exonuclease 3''-5'' domain-like-containing protein 2; exonuclease 3'-5' domain-like 2; FLJ10738; RGD1311087
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Epigenetics and Nuclear Signaling
Purification
Antigen affinity purification
Concentration
0.96 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:40-1:200
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
70 kDa
Observed Molecular Weight
Refer to figures
Isotype
IgG
Available Sizes
Curated Selection
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