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TCAP Polyclonal Antibody

Product Specifications

Background

Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G.

Abbreviation

TCAP

UniProt

O15273

Host

Rabbit

Reactivity

Human; Mouse

Immunogen

Fusion protein of human TCAP

Target

19 kDa sarcomeric protein ; CMD1N; CMH25; LGMD2G; Limb girdle muscular dystrophy 2G (autosomal recessive) ; T-cap; Tcap; TELE; Telethonin; TELT; Titin cap protein; Titin-cap

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Cancer; Cardiovascular

Purification

Antigen affinity purification

Concentration

1.02 mg/mL

Dilution

IHC 1:50-1:200

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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