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PBXIP1 Polyclonal Antibody

Product Specifications

Background

The protein encoded by this gene interacts with the PBX1 homeodomain protein, inhibiting its transcriptional activation potential by preventing its binding to DNA. The encoded protein, which is primarily cytosolic but can shuttle to the nucleus, also can interact with estrogen receptors alpha and beta and promote the proliferation of breast cancer, brain tumors, and lung cancer. Several transcript variants encoding different isoforms have been found for this gene. More variants exist, but their full-length natures have yet to be determined.

Abbreviation

PBXIP1

UniProt

Q96AQ6

Host

Rabbit

Reactivity

Human

Immunogen

Fusion protein of human PBXIP1

Target

4732463H20Rik; Hematopoietic PBX interacting protein ; HPIP ; MGC38361; Pre B cell leukemia homeobox interacting protein 1; RP11-307C12.2

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Epigenetics and Nuclear Signaling; Signal transduction

Purification

Antigen affinity purification

Concentration

0.66 mg/mL

Dilution

IHC 1:40-1:200

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Citation 01

https://www.ncbi.nlm.nih.gov/pmc/articles/pmc8273515/

Isotype

IgG

Available Sizes

Frequently Asked Questions

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