ARMC8 Polyclonal Antibody
Product Specifications
Background
The armadillo (ARM) repeat family of proteins are related to the Drosophila melanogaster armadillo protein, a protein essential for wingless signal transduction. ARM proteins are involved in a variety of processes such as cell migration, cell proliferation, tissue maintenance and tumorigenesis, and they also function in signal transduction and the maintenance of overall cell structure. ARMC8 (armadillo repeat containing 8), also known as S863-2, is a 673 amino acid protein that contains 14 ARM repeats, suggesting a role in signal transduction events throughout the cell. Six isoforms of ARMC8 are expressed due to alternative splicing events. The gene encoding ARMC8 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci.
Abbreviation
ARMC8
UniProt
Q8IUR7
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Fusion protein of human ARMC8
Target
Armadillo repeat containing protein 8; Armadillo repeat-containing protein 8; ARMC8; ARMC8; HSPC056; MGC10058; MGC4880; S863 2
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Epigenetics and Nuclear Signaling
Purification
Antigen affinity purification
Concentration
0.66 mg/mL
Dilution
IHC 1:40-1:200
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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