HMBS Polyclonal Antibody
Product Specifications
Background
This gene encodes a member of the hydroxymethylbilane synthase superfamily. The encoded protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described.
Abbreviation
HMBS
UniProt
P08397
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Fusion protein of human HMBS
Target
HEM3; HMBS; Hydroxymethylbilane synthase; PBG D; PBG-D; PBGD; PORC; Porphobilinogen deaminase; porphyria; acute; Chester type; Pre uroporphyrinogen synthase; Pre-uroporphyrinogen synthase; UPS; Uroporphyrinogen I synthase; Uroporphyrinogen I synthetase
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Cancer; Cell Biology; Metabolism; Signal Transduction
Purification
Antigen affinity purification
Concentration
1.08 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
39 kDa
Observed Molecular Weight
Refer to figures
Isotype
IgG
Available Sizes
Curated Selection
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