UBXN1 Polyclonal Antibody
Product Specifications
Background
Ubiquitin-binding protein that interacts with the BRCA1-BARD1 heterodimer, and regulates its activity. Specifically binds 'Lys-6'-linked polyubiquitin chains. Interaction with autoubiquitinated BRCA1, leads to inhibit the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer. Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol.
Abbreviation
UBXN1
UniProt
Q04323
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Full length fusion protein
Target
2B28;4930455J02Rik; D19Ertd721e; MGC124706; MGC6696; mY33K; Protein 2B28; RGD1309471; SAKS1; SAPK substrate protein 1; T25529; UBA/UBX 33.3 kDa protein; UBX domain containing protein 1; UBX domain protein 1; UBXD10; UBXN1
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cell Biology; Signal transduction
Purification
Antigen affinity purification
Concentration
1.2 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:40-1:200
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
33 kDa
Observed Molecular Weight
Refer to figures
Isotype
IgG
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
KN219758LP 1 Kit
Acid sphingomyelinase (SMPD1) Human Gene Knockout Kit (CRISPR)
Sign In for Pricing
View Details 
BNC880701-100 1x 100 µL
Melanoma Marker (HMB45 + M2-7C10 + M2-9E3 + T311), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 