DENND1B Polyclonal Antibody
Product Specifications
Background
Clathrin (see MIM 118955) -mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1B, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2; see MIM 601024) . Thus, connecdenns link RAB35 activation with the clathrin machinery.
Abbreviation
DENND1B
UniProt
Q6P3S1
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Fusion protein of human DENND1B
Target
C1ORF18; C1orf218 ; Chromosome 1 open reading frame 218; Connecdenn 2; DEN1B; DENN domain containing protein 1B; DENN domain-containing protein 1B; DENN MADD domain containing 1B; DENND1B; DKFZp547O0715; FAM31B ; Family with sequence similarity 31 member B; FLJ20054; FLJ21179 ; FLJ33888; MGC103810; MGC27044; Protein FAM31B; RP11 53I24.2
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Cell Biology
Purification
Antigen affinity purification
Concentration
0.54 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product Datasheet
https://789.bio/ea/w5hdv9
Product MSDS
https://789.bio/eb/qHK8m5
Calculated Molecular Weight
86 kDa
Observed Molecular Weight
Refer to figures
Isotype
IgG
Available Sizes
Curated Selection
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