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DDX59 Polyclonal Antibody

Product Specifications

Background

DEAD-box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure and ribosome/spliceosome assembly. Based on their distribution patterns, some members of this family may be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX59 (DEAD box protein 59), also known as ZNHIT5 (zinc finger HIT domaincontaining protein 5), is a 619 amino acid member of the DEAD box helicase protein family. Like many DEAD box helicase family members, DDX59 contains a Q motif, which controls ATP binding and hydrolysis. Expressed as two isoforms produced by alternative splicing, DDX59 contains one helicase C-terminal domain and one HIT-type zinc finger.

Abbreviation

DDX59

UniProt

Q5T1V6

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Fusion protein of human DDX59

Target

DDX 59; DDX59; DDX59; DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 ; DEAD box protein 59; DKFZP564B1023; OTTHUMP00000033840; OTTHUMP00000033841; Probable ATP-dependent RNA helicase DDX59; RP11-92G12.2; Zinc finger HIT domain containing protein 5 ; Zinc finger HIT domain-containing protein 5; ZNHIT5

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Epigenetics and Nuclear Signaling

Purification

Antigen affinity purification

Concentration

1.02 mg/mL

Dilution

WB 1:500-1:2000; IHC 1:30-1:150

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

69 kDa

Observed Molecular Weight

Refer to figures

Isotype

IgG

Available Sizes

Curated Selection

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