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TBCB Polyclonal Antibody

Product Specifications

Background

Microtubules, the primary component of the cytoskeletal network, are highly dynamic structures composed of α/β Tubulin heterodimers. Biosynthesis of functional microtubules involve the participation of several chaperones, termed Tubulin folding cofactors A (TBCA), B (TBCB), D (TBCD), E (TBCE) and C (TBCC), that act on folding intermediates downstream of the cytosolic chaperon, alternatively named TCP. TBCB (tubulin folding cofactor B), also known as CG22, CKAP1 or CKAPI, is a 244 amino acid cytoplasmic protein containing one CAP-Gly domain and in widely expressed. TBCB is involved in the regulation of tubulin heterodimer dissociation and may function as a negative regulator of axonal growth.

Abbreviation

TBCB

UniProt

Q99426

Host

Rabbit

Reactivity

Human; Mouse

Immunogen

Full length fusion protein

Target

CG22; CKAPI; Cytoskeleton associated protein 1; Cytoskeleton associated protein CKAPI; Cytoskeleton-associated protein 1; Cytoskeleton-associated protein CKAPI; Tbcb; TBCB; Tubulin folding cofactor B; Tubulin specific chaperone B; Tubulin-folding cofactor B; Tubulin-specific chaperone B

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Neuroscience; Signal transduction

Purification

Antigen affinity purification

Concentration

0.78 mg/mL

Dilution

WB 1:500-1:2000; IHC 1:20-1:100

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

27 kDa

Observed Molecular Weight

Refer to figures

Isotype

IgG

Available Sizes

Curated Selection

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