TBCB Polyclonal Antibody
Product Specifications
Background
Microtubules, the primary component of the cytoskeletal network, are highly dynamic structures composed of α/β Tubulin heterodimers. Biosynthesis of functional microtubules involve the participation of several chaperones, termed Tubulin folding cofactors A (TBCA), B (TBCB), D (TBCD), E (TBCE) and C (TBCC), that act on folding intermediates downstream of the cytosolic chaperon, alternatively named TCP. TBCB (tubulin folding cofactor B), also known as CG22, CKAP1 or CKAPI, is a 244 amino acid cytoplasmic protein containing one CAP-Gly domain and in widely expressed. TBCB is involved in the regulation of tubulin heterodimer dissociation and may function as a negative regulator of axonal growth.
Abbreviation
TBCB
UniProt
Q99426
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Full length fusion protein
Target
CG22; CKAPI; Cytoskeleton associated protein 1; Cytoskeleton associated protein CKAPI; Cytoskeleton-associated protein 1; Cytoskeleton-associated protein CKAPI; Tbcb; TBCB; Tubulin folding cofactor B; Tubulin specific chaperone B; Tubulin-folding cofactor B; Tubulin-specific chaperone B
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Neuroscience; Signal transduction
Purification
Antigen affinity purification
Concentration
0.78 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:20-1:100
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
27 kDa
Observed Molecular Weight
Refer to figures
Isotype
IgG
Available Sizes
Curated Selection
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