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GARS Polyclonal Antibody

Product Specifications

Background

This gene encodes glycyl-tRNA synthetase, one of the aminoacyl-tRNA synthetases that charge tRNAs with their cognate amino acids. The encoded enzyme is an (alpha) 2 dimer which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Two transcript variants encoding different isoforms have been found for this gene.

Abbreviation

GARS

UniProt

P41250

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Fusion protein of human GARS

Target

AP 4 A synthetase; Charcot Marie Tooth neuropathy 2D; Charcot Marie Tooth neuropathy neuronal type D; CMT2D ; Diadenosine tetraphosphate synthetase; DSMAV ; EC 6.1.1.14; Glycine tRNA ligase; Glycyl tRNA synthetase; GlyRS ; HMN5; SMAD1

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB

Field of Research

Cancer; Epigenetics and Nuclear Signaling

Purification

Antigen affinity purification

Concentration

0.6 mg/mL

Dilution

WB 1:500-1:2000

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Product Datasheet

https://789.bio/ea/hm14xl

Product MSDS

https://789.bio/eb/q98aXD

Calculated Molecular Weight

83 kDa

Observed Molecular Weight

Refer to figures

Isotype

IgG

Available Sizes

Curated Selection

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