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VTI1A Polyclonal Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the family of soluble N-ethylmaleimide-sensitive fusion protein-attachment protein receptors (SNAREs) that function in intracellular trafficking. This family member is involved in vesicular transport between endosomes and the trans-Golgi network. It is a vesicle-associated SNARE (v-SNARE) that interacts with target membrane SNAREs (t-SNAREs) . Polymorphisms in this gene have been associated with binocular function, and also with susceptibility to colorectal and lung cancers. A recurrent rearrangement has been found between this gene and the transcription factor 7-like 2 (TCF7L2) gene in colorectal cancers. Alternative splicing results in multiple transcript variants.

Abbreviation

VTI1A

UniProt

Q96AJ9

Host

Rabbit

Reactivity

Human; Mouse

Immunogen

Full length fusion protein

Target

MMDS3; MVti1; SNARE Vti1a beta protein ; Vesicle transport through interaction with t-SNAREs homolog 1A; Vesicle transport through interaction with tSNAREs homolog 1A (yeast) ; Vesicle transport v-SNARE protein Vti1-like 2; Vti1 rp2; Vti1-rp2; Vti1a; VTI1A vesicle transport through interaction with t-SNAREs 1A; VTI1A; VTI1RP2

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Neuroscience; Signal transduction

Purification

Antigen affinity purification

Concentration

0.5 mg/mL

Dilution

WB 1:500-1:2000; IHC 1:25-1:100

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

25 kDa

Observed Molecular Weight

Refer to figures

Isotype

IgG

Available Sizes

Frequently Asked Questions

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