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VCP Polyclonal Antibody

Product Specifications

Background

VCP (Valosin-containing protein) belongs to the AAA ATPase family.VCP was first identified as a result of attempts to clone a putative peptide hormone called valosin. It was found that the cloned cDNA encoded a ubiquitously expressed 90 kDa cytosolic protein, termed VCP, which showed none of the characteristics of a peptide hormone precursor.Defects in VCP are the cause of inclusion body myopathy with early-onset Paget disease and frontotemporal dementia (IBMPFD) and amyotrophic lateral sclerosis type 14 with or without frontotemporal dementia (ALS14)

Abbreviation

VCP

UniProt

P55072

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Fusion protein of human VCP

Target

15S Mg (2+) ATPase p97 subunit;15S Mg (2+) -ATPase p97 subunit; ALS14; ATPase p97; CDC48; IBMPFD; MGC131997; MGC148092; MGC8560; p97; TER ATPase; TERA; TERA; Transitional endoplasmic reticulum ATPase; Valosin containing protein; Valosin-containing protein; VCP; Yeast Cdc48p homolog

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Cancer; Metabolism; Neuroscience; Signal Transduction

Purification

Antigen affinity purification

Concentration

0.5 mg/mL

Dilution

WB 1:500-1:2000; IHC 1:30-1:150

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

89 kDa

Observed Molecular Weight

Refer to figures

Isotype

IgG

Available Sizes

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