ZFP36 Polyclonal Antibody
Product Specifications
Background
MRNA-binding protein involved in post-transcriptional regulation of AU-rich element (ARE) -containing mRNAs. Acts by specifically binding ARE-containing mRNAs and promoting their degradation. Recruits deadenylase CNOT7 (and probably the CCR4-NOT complex) via association with CNOT1. Plays a key role in the post-transcriptional regulation of tumor necrosis factor (TNF) . Plays a key role in the post-transcriptional regulation of tumor necrosis factor (TNF) .
Abbreviation
ZFP36
UniProt
P26651
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Fusion protein of human ZFP36
Target
G0/G1 switch regulatory protein 24; G0S24; GOS24; Growth factor-inducible nuclear protein NUP475; NUP475; Protein TIS11A; RNF162A; TIS 11; TIS11; TIS11A; Tristetraprolin; Tristetraproline; TTP; TTP; Zfp-36; ZFP36; Zinc finger protein 36; Zinc finger protein 36 homolog; Zinc finger protein 36; C3H type; homolog (mouse) ; Zinc finger protein; C3H type; 36 homolog
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Epigenetics and Nuclear Signaling; Immunology; Neuroscience; Signal transduction
Purification
Antigen affinity purification
Concentration
0.7 mg/mL
Dilution
IHC 1:30-1:150
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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