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TNNC1 Polyclonal Antibody

Product Specifications

Background

Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension.

Abbreviation

TNNC1

UniProt

P63316

Host

Rabbit

Reactivity

Human; Mouse

Immunogen

Full length fusion protein

Target

Tnnc1a; Cardiac troponin C; slow skeletal and cardiac muscles; TN-C; TNC; Tnnc1; TNNC1; TNNI3; Troponin C; Troponin C slow; Troponin C1 slow

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Cancer; Cardiovascular; Signal Transduction

Purification

Antigen affinity purification

Concentration

0.8 mg/mL

Dilution

WB 1:500-1:2000; IHC 1:10-1:50

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Product Datasheet

https://789.bio/ea/le1g48

Product MSDS

https://789.bio/eb/H4iD4O

Calculated Molecular Weight

18 kDa

Observed Molecular Weight

Refer to figures

Citation 01

https://link.springer.com/article/10.1007/s11356-022-24656-4

Isotype

IgG

Available Sizes

Curated Selection

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