IDO2 Polyclonal Antibody

INDOL1 is also known as IDO2 (indoleamine 2,3-dioxygenase 2) and is a 407 amino acid protein that is expressed in various tissues, including liver, small intestine, spleen, placenta, thymus, lung, brain, kidney, colon and dendritic cells. INDOL1 is selectively inhibited by D-1MT (1-methyl-d-tryptophan), which also inhibits IDO (indoleamine 2,3-dioxygenase) and is significant because IDO expression causes suppression of T cell responses to tumors in dendritic cells. The inhibition of INDOL1 by D-1MT suggests a common function in immunomodulation. In the human INDOL1 gene, two single nucleotide polymorphisms have been detected which abolish the enzymatic function of INDOL1.

3-dioxygenase 2;3-dioxygenase-like protein 1; EC 1.13.11.; I23O2; IDO 2; IDO-2; Ido2; INDOL 1; Indoleamine 2; Indoleamine 2;3 dioxygenase 2; Indoleamine 2;3 dioxygenase like 1 protein; Indoleamine 2;3 dioxygenase like protein 1; Indoleamine pyrrole 2;3 dioxygenase like 1; Indoleamine pyrrole 2;3 dioxygenase like protein 1; Indoleamine-pyrrole 2