IDO2 Polyclonal Antibody
Product Specifications
Background
INDOL1 is also known as IDO2 (indoleamine 2,3-dioxygenase 2) and is a 407 amino acid protein that is expressed in various tissues, including liver, small intestine, spleen, placenta, thymus, lung, brain, kidney, colon and dendritic cells. INDOL1 is selectively inhibited by D-1MT (1-methyl-d-tryptophan), which also inhibits IDO (indoleamine 2,3-dioxygenase) and is significant because IDO expression causes suppression of T cell responses to tumors in dendritic cells. The inhibition of INDOL1 by D-1MT suggests a common function in immunomodulation. In the human INDOL1 gene, two single nucleotide polymorphisms have been detected which abolish the enzymatic function of INDOL1.
Abbreviation
IDO2
UniProt
Q6ZQW0
Host
Rabbit
Reactivity
Human
Immunogen
Full length fusion protein
Target
3-dioxygenase 2;3-dioxygenase-like protein 1; EC 1.13.11.; I23O2; IDO 2; IDO-2; Ido2; INDOL 1; Indoleamine 2; Indoleamine 2;3 dioxygenase 2; Indoleamine 2;3 dioxygenase like 1 protein; Indoleamine 2;3 dioxygenase like protein 1; Indoleamine pyrrole 2;3 dioxygenase like 1; Indoleamine pyrrole 2;3 dioxygenase like protein 1; Indoleamine-pyrrole 2
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Metabolism; Signal Transduction
Purification
Antigen affinity purification
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:30-1:150
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
45 kDa
Observed Molecular Weight
Refer to figures
Isotype
IgG
Available Sizes
Frequently Asked Questions
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