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XRCC4 Polyclonal Antibody

Product Specifications

Background

The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks. This protein plays a role in both non-homologous end joining and the completion of V (D) J recombination. Mutations in this gene can cause short stature, microcephaly, and endocrine dysfunction (SSMED) . Alternative splicing generates several transcript variants.

Abbreviation

XRCC4

UniProt

Q13426

Host

Rabbit

Reactivity

Human

Immunogen

Fusion protein of human XRCC4

Target

DNA double strand break repair and V (D) J recombination protein XRCC4; DNA repair protein XRCC4; SSMED; X ray repair complementing defective repair in Chinese hamster cells 4; X ray repair cross complementing 4; X ray repair cross complementing protein 4; X-ray repair cross-complementing protein 4; XRCC 4; XRCC4; XRCC4

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Cancer; Epigenetics and Nuclear Signaling

Purification

Antigen affinity purification

Concentration

1.08 mg/mL

Dilution

IHC 1:50-1:200

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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