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BDNF Polyclonal Antibody

Product Specifications

Background

BDNF is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of BDNF is reduced in both Alzheimer's and Huntington disease patients. It play a role in the regulation of stress response and in the biology of mood disorders.

Abbreviation

BDNF

UniProt

P23560

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Fusion protein of human BDNF

Target

Abrineurin; ANON2; BDNF; BDNF; Brain Derived Neurotrophic Factor; Brain-derived neurotrophic factor; BULN2; MGC34632; Neurotrophin

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Cancer; Cardiovascular; Metabolism; Neuroscience

Purification

Antigen affinity purification

Concentration

1.14 mg/mL

Dilution

WB 1:500-1:2000; IHC 1:50-1:100

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Product Datasheet

https://789.bio/ea/lml484

Product MSDS

https://789.bio/eb/mLGy50

Calculated Molecular Weight

28 kDa

Observed Molecular Weight

Refer to figures

Citation 01

https://pubs.rsc.org/en/content/articlelanding/2022/fo/d2fo00423b

Citation 02

https://link.springer.com/article/10.1007/s12035-022-03026-8

Citation 03

https://www.hindawi.com/journals/omcl/2018/4572893/abs/

Citation 04

https://pubs.acs.org/doi/abs/10.1021/acschemneuro.1c00648

Citation 05

https://link.springer.com/article/10.1007/s00213-021-05996-4

Citation 06

https://link.springer.com/article/10.1007/s12640-021-00467-2

Citation 07

https://www.liebertpub.com/doi/abs/10.1089/jmf.2021.0154

Isotype

IgG

Available Sizes

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