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EARS2 Polyclonal Antibody

Product Specifications

Background

This gene encodes a member of the class I family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. This protein is encoded by the nuclear genome but is likely to be imported to the mitochondrion where it is thought to catalyze the ligation of glutamate to tRNA molecules. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency 12 (COXPD12) . Alternative splicing results in multiple transcript variants.

Abbreviation

EARS2

UniProt

Q5JPH6

Host

Rabbit

Reactivity

Human; Mouse

Immunogen

Synthetic peptide of human EARS2

Target

3230401I01Rik; AL024049; COXPD12; EARS 2; ears2; GluRS; Glutamate--tRNA ligase; Glutamyl tRNA synthetase 2 mitochondrial; mitochondrial; mKIAA1970; MSE1; Probable glutamyl tRNA synthetase; mitochondrial ; Probable glutamyl-tRNA synthetase; RGD1307904; SYEM

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Epigenetics and Nuclear Signaling; Metabolism; Signal transduction

Purification

Antigen affinity purification

Concentration

0.9 mg/mL

Dilution

IHC 1:50-1:100

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG

Available Sizes

Frequently Asked Questions

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