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EN2 Polyclonal Antibody

Product Specifications

Background

Homeobox-containing genes are thought to have a role in controlling development. In Drosophila, the 'engrailed' (en) gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal. The human engrailed homologs 1 and 2 encode homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system.

Abbreviation

EN2

UniProt

P19622

Host

Rabbit

Reactivity

Human; Mouse

Immunogen

Synthetic peptide of human EN2

Target

AUTS 1; AUTS1; EN 2; Engrailed 2; Engrailed homeo box 2; Engrailed homeobox 2; Engrailed homolog 2; Engrailed2; Homeobox protein engrailed 2; Homeobox protein engrailed2; Hu En 2 ; HuEn2; MabEn

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB

Field of Research

Cancer; Epigenetics and Nuclear Signaling; Neuroscience; Stem cells

Purification

Antigen affinity purification

Concentration

0.96 mg/mL

Dilution

WB 1:500-1:2000

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

34 kDa

Observed Molecular Weight

Refer to figures

Isotype

IgG

Available Sizes

Curated Selection

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