DMGDH Polyclonal Antibody
Product Specifications
Background
This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum. Alternative splicing results in multiple transcript variants.
Abbreviation
DMGDH
UniProt
Q9UI17
Host
Rabbit
Reactivity
Human
Immunogen
Synthetic peptide of human DMGDH
Target
Dimethylglycine dehydrogenase; Dimethylglycine dehydrogenase; mitochondrial; Dmgdh; M2GD; ME2GLYDH; mitochondrial
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Metabolism; Neuroscience; Signal Transduction
Purification
Antigen affinity purification
Concentration
2.1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product Datasheet
https://789.bio/ea/med4dh
Product MSDS
https://789.bio/eb/CG4u50
Calculated Molecular Weight
97 kDa
Observed Molecular Weight
Refer to figures
Isotype
IgG
Available Sizes
Curated Selection
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