UCN3 Polyclonal Antibody
Product Specifications
Background
This gene encodes a member of the sauvagine/corticotropin-releasing factor/urotensin I family of proteins. The encoded preproprotein is proteolytically processed to generate the mature peptide hormone, which is secreted by pancreatic beta and alpha cells. This hormone is an endogenous ligand for corticotropin-releasing factor receptor 2 and may regulate insulin secretion in response to plasma glucose levels. Patients with type 2 diabetes exhibit reduced levels of the encoded protein in beta cells. In the brain, the encoded protein may be responsible for the effects of stress on appetite.
Abbreviation
UCN3
UniProt
Q969E3
Host
Rabbit
Reactivity
Human
Immunogen
Synthetic peptide of human UCN3
Target
MGC119002; OTTHUMP00000018999 ; Prepro urocortin 3; SCP; SPC; Stresscopin ; Ucn III ; UCN3 ; UCN3 urocortin 3 stresscopin; UCNIII; Urocortin 3; Urocortin 3 stresscopin; Urocortin III
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Cardiovascular; Metabolism; Neuroscience; Signal transduction
Purification
Antigen affinity purification
Concentration
1.4 mg/mL
Dilution
IHC 1:50-1:300
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG
Available Sizes
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