LRRC16A Polyclonal Antibody
Product Specifications
Background
Cell membrane-cytoskeleton-associated protein that plays a role in the regulation of actin polymerization at the barbed end of actin filaments. Prevents F-actin heterodimeric capping protein (CP) activity at the leading edges of migrating cells, and hence generates uncapped barbed ends and enhances actin polymerization, however, seems unable to nucleate filaments (PubMed:16054028) . Plays a role in lamellipodial protrusion formations and cell migration (PubMed:19846667) .
Abbreviation
LRRC16A
UniProt
Q5VZK9
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Synthetic peptide of human LRRC16A
Target
Acan 125; Capping protein; Arp2/3; and myosin I linker; CARMIL homolog; leucine rich repeat containing 16; Leucine-rich repeat-containing protein 16A; LR16A; Lrrc16 protein; LRRC16A; p116
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Signal transduction
Purification
Antigen affinity purification
Concentration
0.6 mg/mL
Dilution
IHC 1:30-1:150
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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