CYP11B2 Polyclonal Antibody
Product Specifications
Background
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency.
Abbreviation
CYP11B2
UniProt
P19099
Host
Rabbit
Reactivity
Human
Immunogen
Synthetic peptide of human CYP11B2
Target
ALDOS; Aldosterone synthase; Aldosterone-synthesizing enzyme; C11B2; CYP11B2; CYPXIB2; Cytochrome P-450Aldo; Cytochrome P-450C18; Cytochrome P450 11B2; Cytochrome P450 11B2; mitochondrial; mitochondrial; P-450Aldo; P-450C18; Steroid 18-hydroxylase
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Cardiovascular; Metabolism
Purification
Antigen affinity purification
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:50-1:300
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
58 kDa
Observed Molecular Weight
Refer to figures
Isotype
IgG
Available Sizes
Curated Selection
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