AHR activator 1
AHR activator 1 is an aryl hydrocarbon receptor activator with activity regulating fibroblast growth factor-2 (FGF2) -induced branching morphogenesis. AHR activator 1 prevents the formation of cellular branches by inhibiting AHR signaling. AHR activator 1 also associates with adhesion of dissociated linkers, suggesting the importance of dissociated linkers in the inhibition of branching by AHR agonists. Studies of AHR activator 1 reveal its functional role in mammary gland morphogenesis and play a role in inhibiting FGF-induced invasion[1].
Product Specifications
CAS Number
[352346-46-4]
UNSPSC
12352005
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ahr-activator-1.html
Smiles
ClC1=CC=C(C(Cl)=C1)C2=NC(C3=CC=CC=C3)=NO2
Molecular Formula
C14H8Cl2N2O
Molecular Weight
291.13
References & Citations
[1]Chemical genetic screen reveals a role for desmosomal adhesion in mammary branching morphogenesis
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
Canine Helicobacter pylori cytotoxin-associated gene A protein IgG (HP-CagA-IgG) ELISA Kit
