AHR activator 1
Product Specifications
UNSPSC Description
AHR activator 1 is an aryl hydrocarbon receptor activator with activity regulating fibroblast growth factor-2 (FGF2)-induced branching morphogenesis. AHR activator 1 prevents the formation of cellular branches by inhibiting AHR signaling. AHR activator 1 also associates with adhesion of dissociated linkers, suggesting the importance of dissociated linkers in the inhibition of branching by AHR agonists. Studies of AHR activator 1 reveal its functional role in mammary gland morphogenesis and play a role in inhibiting FGF-induced invasion[1].
Target Antigen
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
cancer
Assay Protocol
https://www.medchemexpress.com/ahr-activator-1.html
Smiles
ClC1=CC=C(C(Cl)=C1)C2=NC(C3=CC=CC=C3)=NO2
Molecular Weight
291.13
References & Citations
[1]Chemical genetic screen reveals a role for desmosomal adhesion in mammary branching morphogenesis
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-118792/AHR-activator-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-118792/
Clinical Information
No Development Reported
CAS Number
352346-46-4
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