GHR Polyclonal Antibody

This gene encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature.

GH receptor; GH-binding protein; GHBP; GHBP; included; GHR; GHR; Growth hormone binding protein; Growth hormone receptor; Growth hormone receptor precursor; Growth hormone-binding protein; Growth hormone-binding protein; included; Increased responsiveness to growth hormone; included; Serum binding protein; Serum-binding protein; Somatotropin receptor