TRIB2 Polyclonal Antibody
Product Specifications
Background
This gene encodes one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia. Alternatively spliced transcript variants have been found for this gene.
Abbreviation
TRIB2
UniProt
Q92519
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Full length fusion protein
Target
C5FW; FLJ57420; GS3955; Hypothetical protein TRB2; TRB-2; TRB2; TRIB 2; TRIB2; TRIB2; Tribbles homolog 2
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Cardiovascular; Signal transduction; Stem cells
Purification
Affinity purification
Concentration
0.4 mg/mL
Dilution
IHC 1:30-150
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product Datasheet
https://789.bio/ea/o4d9c0
Product MSDS
https://789.bio/eb/DWPi18
Isotype
IgG
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
