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TM7SF2 Polyclonal Antibody

Product Specifications

Background

Transmembrane 7 superfamily member 2 (TM7SF2, Sterol C14-reductase, 3beta-hydroxysterol Delta-reductase) is a 418 amino acid gene product that belongs to the ERG4/ERG24 family. TM7SF2 is a seven pass transmembrane protein that can localize to the membrane of the endoplasmic reticulum. TM7SF2 is involved in the conversion of lanosterol to cholesterol and, specifically, catalyzes the NADPH dependant reduction of 4,4-dimethyl-5-alpha-cholesta-8,14,24-trien-3-beta-ol to 4,4-dimethyl-5-alpha-cholesta-8,24-dien-3-beta-ol and NADP+.

Abbreviation

TM7SF2

UniProt

O76062

Host

Rabbit

Reactivity

Human; Mouse

Immunogen

Synthetic peptide of human TM7SF2

Target

ANG1; NET47; DHCR14A

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Purification

Affinity purification

Concentration

0.6 mg/mL

Dilution

WB 1:500-1:2000; IHC 1:25-1:100

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Product Datasheet

https://789.bio/ea/5xyym5

Product MSDS

https://789.bio/eb/XjLKqL

Calculated Molecular Weight

46kDa

Isotype

IgG

Available Sizes

Curated Selection

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