TM7SF2 Polyclonal Antibody
Product Specifications
Background
Transmembrane 7 superfamily member 2 (TM7SF2, Sterol C14-reductase, 3beta-hydroxysterol Delta-reductase) is a 418 amino acid gene product that belongs to the ERG4/ERG24 family. TM7SF2 is a seven pass transmembrane protein that can localize to the membrane of the endoplasmic reticulum. TM7SF2 is involved in the conversion of lanosterol to cholesterol and, specifically, catalyzes the NADPH dependant reduction of 4,4-dimethyl-5-alpha-cholesta-8,14,24-trien-3-beta-ol to 4,4-dimethyl-5-alpha-cholesta-8,24-dien-3-beta-ol and NADP+.
Abbreviation
TM7SF2
UniProt
O76062
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Synthetic peptide of human TM7SF2
Target
ANG1; NET47; DHCR14A
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Purification
Affinity purification
Concentration
0.6 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:25-1:100
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
46kDa
Isotype
IgG
Available Sizes
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