ACTN2 Polyclonal Antibody
Product Specifications
Background
Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein witHuman, Mouseultiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smootHuman, Mouseuscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments.
Abbreviation
ACTN2
UniProt
P35609
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Synthetic peptide of human ACTN2
Target
Actin binding protein; Actinin alpha 2; ACTN 2; ACTN2; ACTN2; Alpha actinin 2; Alpha actinin skeletal muscle; Alpha actinin skeletal muscle isoform 2; Alpha-actinin skeletal muscle isoform 2; Alpha-actinin-2; CMD1AA; F actin cross linking protein; F-actin cross-linking protein
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Cardiovascular; Signal transduction
Purification
Affinity purification
Concentration
0.4 mg/mL
Dilution
WB 1:1000-1:5000; IHC 1:25-1:100
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product Datasheet
https://789.bio/ea/8k084k
Product MSDS
https://789.bio/eb/f9e1S0
Calculated Molecular Weight
104kDa
Isotype
IgG
Available Sizes
Curated Selection
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