PPOX Polyclonal Antibody
Product Specifications
Background
This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane. Alternatively spliced transcript variants encoding the same protein have been identified.
Abbreviation
PPOX
UniProt
P50336
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Synthetic peptide of human PPOX
Target
MGC8485; PPO; PPOX; PPOX; Protoporphyrinogen oxidase; V290M; Variegate porphyria; VP
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Metabolism; Tags and Cell markers
Purification
Affinity purification
Concentration
0.5 mg/mL
Dilution
WB 1:1000-1:5000; IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
51kDa
Isotype
IgG
Available Sizes
Curated Selection
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