PPM1F Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase.
Abbreviation
PPM1F
UniProt
P49593
Host
Rabbit
Reactivity
Human
Immunogen
Synthetic peptide of human PPM1F
Target
Ca (2+) /calmodulin-dependent protein kinase phosphatase; CaM-kinase phosphatase; CAMKP; CaMKPase; FEM 2; hFEM-2; KIAA0015; Partner of PIX 2; POPX2; PP2C phosphatase; Ppm1f; PPM1F; Protein fem-2 homolog; Protein phosphatase 1F (PP2C domain containing) ; Protein phosphatase 1F; Protein phosphatase Mg2+/Mn2+ dependent 1F
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cell biology; Signal transduction
Purification
Affinity purification
Concentration
0.8 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
50kDa
Isotype
IgG
Available Sizes
Curated Selection
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